Applied Bioinformatics Group


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Welcome to the Kohlbacher lab!


Group Photo

The group of Oliver Kohlbacher was established in 2003 and is primarily working on computer-aided drug design, immunoinformatics, structural bioinformatics as well as bioinformatics applications in proteomics, metabolomics and systems biology. The group collaborates closely with a large number of experimental groups to gain access to up-to-date and relevant datasets.

Besides classical structural bioinformatics methods, we are focused on the use of combinatorial optimization, graph theoretic approaches and machine learning. To make the methods we develop accessible to a larger audience, we contribute to several larger open-source software projects, e.g., BALL (structural bioinformatics), OpenMS (proteomics) and BN++/BiNA (network analysis).

Most recent publications:

Junker, J, Bielow, C, Bertsch, A, Sturm, M, Reinert, K, and Kohlbacher, O (accepted). TOPPAS: A graphical workflow editor for the analysis of high-throughput proteomics data. J. Proteome Res..

Röglin, L, Thiel, P, Kohlbacher, O, and Ottmann, C (accepted). Covalent attachment of pyridoxal-phosphate derivatives to 14-3-3 proteins. Proc. Natl. Acad. Sci. USA.

Recent news:

Nora Toussaint received her PhD: We are pleased to congratulate Dr. Nora C. Toussaint on passing her PhD exam and wish her all the best for the future.

Sebastian Briesemeister received his PhD: We are pleased to congratulate Dr. Sebastian Briesemeister on passing his PhD exam and wish him all the best for the future.